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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DKC1
All Species:
30
Human Site:
S255
Identified Species:
47.14
UniProt:
O60832
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60832
NP_001354.1
514
57674
S255
R
V
R
S
G
V
M
S
E
K
D
H
M
V
T
Chimpanzee
Pan troglodytes
XP_521345
595
65925
S336
R
V
R
S
G
V
M
S
E
K
D
H
M
V
T
Rhesus Macaque
Macaca mulatta
XP_001090867
597
66468
S338
R
V
R
S
G
V
M
S
E
K
D
H
M
V
T
Dog
Lupus familis
XP_549382
517
57997
S255
R
V
R
S
G
V
M
S
E
K
D
H
M
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESX5
509
57483
S255
R
V
R
S
G
V
M
S
E
K
D
H
M
V
T
Rat
Rattus norvegicus
P40615
509
56597
G256
R
V
R
S
G
V
V
G
E
R
D
H
M
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514686
519
58453
G257
R
V
R
S
G
V
M
G
E
K
D
H
M
V
T
Chicken
Gallus gallus
Q5ZJH9
516
58132
G253
R
V
R
S
G
I
L
G
E
M
D
N
M
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001028279
506
56658
G250
R
V
R
S
G
V
L
G
E
K
D
N
L
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O44081
508
56812
S253
R
V
R
S
G
I
Q
S
E
R
D
G
M
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17919
445
50192
M201
E
Y
D
P
A
Q
Q
M
G
I
F
N
C
I
C
Sea Urchin
Strong. purpuratus
XP_001187533
541
60439
S248
R
V
R
S
G
I
Q
S
E
K
E
A
L
V
T
Poplar Tree
Populus trichocarpa
XP_002323264
482
54054
R235
G
H
M
Q
E
L
R
R
V
R
S
G
I
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD90
565
63008
G246
R
V
R
S
G
I
L
G
E
N
N
N
M
V
T
Baker's Yeast
Sacchar. cerevisiae
P33322
483
54686
S225
R
V
R
S
G
A
L
S
E
N
D
N
M
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
85.5
89.9
N.A.
90
83.2
N.A.
85.3
81.4
N.A.
74.7
N.A.
64.7
N.A.
58.7
64.8
Protein Similarity:
100
85.3
86
93.6
N.A.
93.1
90.8
N.A.
88.8
89.9
N.A.
85.4
N.A.
77.6
N.A.
71.4
77
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
93.3
66.6
N.A.
73.3
N.A.
73.3
N.A.
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
93.3
N.A.
86.6
N.A.
13.3
86.6
Percent
Protein Identity:
61.2
N.A.
N.A.
57.5
57.9
N.A.
Protein Similarity:
76.4
N.A.
N.A.
73.4
71.9
N.A.
P-Site Identity:
0
N.A.
N.A.
60
73.3
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
74
0
0
0
0
% D
% Glu:
7
0
0
0
7
0
0
0
87
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
0
0
87
0
0
34
7
0
0
14
0
0
7
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
47
0
0
0
% H
% Ile:
0
0
0
0
0
27
0
0
0
7
0
0
7
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
7
27
0
0
0
0
0
14
7
0
% L
% Met:
0
0
7
0
0
0
40
7
0
7
0
0
74
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
14
7
34
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
7
20
0
0
0
0
0
0
0
0
% Q
% Arg:
87
0
87
0
0
0
7
7
0
20
0
0
0
0
0
% R
% Ser:
0
0
0
87
0
0
0
54
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
87
% T
% Val:
0
87
0
0
0
54
7
0
7
0
0
0
0
87
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _